Houston Methodist. Leading Medicine

Hand FAQ


About a year ago I was diagnosed with a hand condition called Dupuytren's disease. I had surgery to fix it and I've been fine ever since. Now I'm noticing some tiny bumps over the backs of my knuckles on the same hand. Is this from Dupuytren's too?


It could be but a doctor would need to examine you to confirm it. Dupuytren's is a connective tissue disorder. Thick, scar-like tissue develops in the palm of the hand. It can affect one or more fingers, pulling them into a flexed position.

When changes occur from Dupuytren's along the backs of the hands it's called Garrod's nodes. At first this can look like bumps or nodules. The same problem can affect the penis, called Peyonie's disease. If the bottom of the feet start to tighten up with fibrous scarring, it's called Ledderhose's disease. Each of these problems can be disabling.

These three conditions are all part of the same disease process. No one knows yet why it happens or how to cure it. Treatment is most often surgical. There's no known drug to treat or cure this problem whether it affects the hands, feet, or penis.

Sandip Hindocha, MBChB, et al. The Heritability of Dupuytren's Disease: Familial Aggregation and Its Clinical Significance. In The Journal of Hand Surgery. February 2006. Vol. 31A. No. 2. Pp. 204-210.

*Disclaimer:* The information contained herein is compiled from a variety of sources. It may not be complete or timely. It does not cover all diseases, physical conditions, ailments or treatments. The information should NOT be used in place of visit with your healthcare provider, nor should you disregard the advice of your health care provider because of any information you read in this topic.
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