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The Effect of Sterilization on Long-Term Wear of an Artificial Hip Joint

Do some total hip replacements last longer because of the way they are sterilized before packaging? This is the question studied by researchers at the Anderson Orthopaedic Research Institute in Virginia.

The authors looked at the rate of wear for two different hip implants. They followed patients for up to 16 years. Sterilization is used to kill any bacteria or viruses in the materials. One group of implants was sterilized using gamma rays (irradiation). The second group was sterilized using ethylene oxide, a chemical that treats the surface of the implant.

Before starting the study, the scientists thought there could be three possible results:

  • Overall wear rates would be about the same, but differences would occur from patient
    to patient.

  • Most patients would have an increase in wear rates the longer they had the implant.

  • Only a small number of patients would have more and more wear many years after getting the implant.

    They found that the first theory was correct. There were no real differences in wear rates regardless of the type of sterilization process used. The wear rates were about the same, even years later.

    The researchers plan to keep watching both groups as long as possible. In the meantime, they say the results of their study should help calm patients' fears. A big increase in wear many years after receiving the implant isn't likely.


    Karl F. Orishimo, MS, et al. Long-Term In Vivo Wear Performance of Porous-Coated Acetabular Components Sterilized with Gamma Irradiation in Air or Ethylene Oxide. In The Journal of Arthroplasty. August 2003. Vol. 18. No. 5. Pp. 546-552.

    10/12/2003

    *Disclaimer:* The information contained herein is compiled from a variety of sources. It may not be complete or timely. It does not cover all diseases, physical conditions, ailments or treatments. The information should NOT be used in place of visit with your healthcare provider, nor should you disregard the advice of your health care provider because of any information you read in this topic.
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