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Lower Spine News

Sciatica Random Control Trials

When doctors want to know whether or not a specific treatment is effective, they look at a collection of studies and compare the results. The most reliable data comes from a specific type of study called random controlled trials (RCTs).

In a RCT, patients are assigned to groups randomly. This may be done by putting everyone in one group whose birthday was in an odd year. Everyone born in an even year is assigned to another group. Or a computer program can do it randomly.

Each group is treated differently and the final outcomes are compared. In this news report, six RCTs comparing discectomy to nonsurgical care for painful disc herniation are reviewed. The trials were conducted over a period of 25 years. So they were very different in design and approach.

Although there were many things that couldn't be compared in these six studies, they did agree on the following points:
  • Patients with sciatica do get better
  • Today's results in treating sciatica are much improved over 25 years ago
  • No matter which treatment was used, most patients had positive outcomes
  • Both treatment options appear to be safe; serious complications are rare
  • Surgery does not have to be done right away to have a good result

    It appears from these six studies that surgery gives faster relief from painful symptoms. But long-term results at one, two, four, and 10 years later are no different. None of the six RCTs had a placebo group (patients who thought they were getting treated but were not). That is an important missing link that must be studied in future research.

    What Do Six RCTs Show? In The BACK Letter. July 2007. Vol. 22. No. 7.Pp. 73, 82.


    *Disclaimer:* The information contained herein is compiled from a variety of sources. It may not be complete or timely. It does not cover all diseases, physical conditions, ailments or treatments. The information should NOT be used in place of visit with your healthcare provider, nor should you disregard the advice of your health care provider because of any information you read in this topic.
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